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17th – 18th Century

René-Antoine Ferchault de Réaumur studies the activity of digestive juices

French Physicist, René-Antoine Ferchault de Réaumur was curious about what happens to food when it goes down the digestive tract.  To find out, he fed a crow with chunks of meat in a closed punctured metal capsule.  Since the bird excreted an empty capsule, Réaumur then knew that the food in the digestive tract is not mechanically processed, but dissolved by a certain substance.  Italian Jesuit priest, Lazzaro Spallanzani took the research further and discovered gastric juice.